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LM of cervix showing severe dysplasia (CIN 3)

LM of cervix showing severe dysplasia (CIN 3)

M850/0332

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Credit

DR. E. WALKER / SCIENCE PHOTO LIBRARY DR. E. WALKER / SCIENCE PHOTO LIBRARY

Caption

Severe cervical dysplasia. Light micrograph of a section through human cervical epithelium showing severe dysplasia (abnormal growth) classified as CIN 3. CIN (cervical intraepithelial neoplasia) is the term used to describe malignant changes in the squamous epithelium of the cervix. Here, epithelial cells (upper half of section) are highly dysplastic, being thickened with enlarged and prominent nuclei (dark, round). Cell division is not now confined to the basal (bottom) layer and dysplastic cells have migrated right to the surface. Such changes are referred to as carcinoma in situ. Haematoxylin and eosin stained. Magnification: x200 at 35mm size.

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