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Historical blood transfusion. This is taken from a 1667 book by Johann S. Elsholtz. Early transfusion experiments were often fatal for the patients due to a lack of knowledge about blood itself. Transfusions from animals to humans usually caused death, and human to human transfusions frequently had the same result. It was not until 1901, when Karl Landsteiner discovered the ABO blood groups, that transfusion science truly began. With the discovery of M, N and P groups in the 1920s and Rhesus groups in the 1930s, transfusions were made safe.
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