NIBSC / SCIENCE PHOTO LIBRARY NIBSC / SCIENCE PHOTO LIBRARY
Scanning electron micrograph (SEM) of a macrophage cell moving over a surface. Wandering macrophages are monocytes from circulating blood that function to defend the body against invasion by foreign organisms. Macrophages migrate to tissues, notably to the lymphatic system and lungs; certain types of macrophage migrate to sites of infection. In an active state, as here, the cell spreads out using its frilly cytoplasm as arms to draw itself along the substrate, to seek and engulf particles. In addition to a scavenging role, macrophages can detect antigenic (foreign) substances during the initial stage of the body's immune response. Magnification: x5,000 at 8x10" ,x714 at 35mm size.
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