56.1 MB (5.0 MB compressed)
5464 x 3588 pixels
46.2 x 30.5 cm ⏐ 18.2 x 12.0 in (300dpi)
NANCY KEDERSHA / SCIENCE PHOTO LIBRARY NANCY KEDERSHA / SCIENCE PHOTO LIBRARY
Active macrophages. Immunofluorescent light micrograph of active macrophage white blood cells producing cytokine proteins. The central cell has multiple nuclei (blue). Vaults are red and TIA-1, a protein which stops cytokine overproduction, is yellow/green. Cytokines are released by one cell population in order to influence another. If too much cytokine has been made, TIA-1 stops its production by binding to the mRNA (messenger ribonucleic acid) that codes for it, forming stress bodies (yellow). These macrophages have been activated by exposure to a mock bacterial infection. Macrophages help to kill invading organisms. Magnification: x200 at 5x7cm size.
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