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Egg follicles of the ovary. Light micrograph of a longitudinal section through egg follicles in the human ovary. Egg follicles begin as primordial follicles (small round, at right). They consist of a primary oocyte (with white nucleus) surrounded by flattened cells. When stimulated to develop these follicles form primary egg follicles. Here, three different stages of development of the primary follicle are seen (from right to left). The egg or oocyte enlarges and its surrounding cells become cuboidal & multiply to form an outer zona granulosa. A glycoprotein layer (thin ring) develops between the pale egg (oocyte) and the outer cells. Magnification: x200 at 35mm size.
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