MANFRED KAGE / SCIENCE PHOTO LIBRARY. MANFRED KAGE / SCIENCE PHOTO LIBRARY.
Light micrograph of a human primary follicle (a potential female ovum - egg) in the ovarian cortex. The development of primordial follicles (formed between the 4th and 7th months of foetal development) into primary follicles begins at sexual maturity. In each ovarian cycle up to 20 primordial follicles are activated to form a primary follice: only one will reach full maturity & be released at ovulation. Follicular cells (red dots) proliferate to form a thickened layer, the zona granulosa. The central oocyte (housing the female gamete) is separated from the follicular cells by a glycoprotein layer, the zona pellucida (blue). Magnification: X 25 at 35mm size.
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