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Molecular Model of RANKL

Molecular Model of RANKL

C012/3911

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Credit

SCOTT CAMAZINE / SCIENCE PHOTO LIBRARY SCOTT CAMAZINE / SCIENCE PHOTO LIBRARY

Caption

Ribbon molecular model of RANKL (Receptor Activator for Nuclear Factor {kappa} B Ligand), also known as TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and ODF (osteoclast differentiation factor). RANKL is a molecule important in bone metabolism. This natural and necessary surface-bound molecule activates osteoclasts, cells involved in bone resorption. Overproduction of RANKL is implicated in a variety of degenerative bone diseases, such as rheumatoid arthritis and osteomyelitis. The image shows the 3 protein chains of the molecule.

Release details

Model release not required. Property release not available.

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