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Illustration showing the anatomy of the brain effected by normal pressure hydrocephalus (NPH). Clinical symptoms (abnormal gait, urinary incontinence, and dementia) result from enlarged ventricles (in blue) distorting the central portion of the corona radiata (tinted orange). This could lead to periventricular white matter edema, which controls gait and urinary continence, and dementia occurs when the periventricular limbic system is distorted. Impaired blood flow may be a result of NPH as well. Ventricular enlargement after transient high pressure hydrocephalus may cause cerebrospinal fluid (CSF) readings later to appear within normal range, hence the title normal pressure hydrocephalus. Also pictured is a graphic row of midsagittal MRIs showing the.
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