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New Delhi metallo-beta-lactamase gene

New Delhi metallo-beta-lactamase gene

C012/8031

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Credit

CAROL & MIKE WERNER / VISUALS UNLIMITED, INC. / SCIENCE PHOTO LIBRARY CAROL & MIKE WERNER / VISUALS UNLIMITED, INC. / SCIENCE PHOTO LIBRARY

Caption

Biomedical illustration of a section of Bacteria possessing the New Delhi metallo-beta-lactamase (NDM-1) gene referred to as a Superbug. The NDM-1 gene is not part of the bacteria's genome but lies on plastids which are DNA remnants floating in the cytoplasm. The NDM-1 gene enables production of the NDM-1 enzyme which makes the bacteria resistant to a broad range of antibiotics including those of the carbapenem family. NDM-1 is a carbapenemase beta-lactamase, an enzyme that hydrolyzes and inactivates carbapenems such as imipenem-cilastatin shown here in molecular form.

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