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SCI-VIS IFC-CNR / SCIENCE PHOTO LIBRARY SCI-VIS IFC-CNR / SCIENCE PHOTO LIBRARY
Protein interactions animation. Clip 6 of 10. This clip forms part of an animation sequence showing protein interactions within a dividing cell. This clip shows a molecule of the protein calmodulin (CaM, calcium-modulated protein) surrounded by ions and other small, fast-moving molecules. It is transiting from an unbound state (ApoCaM) to the state in which it is bound to four calcium ions (CaCaM). This process changes the shape (conformation) of the protein, and is an important step that enables this protein to bind to other proteins. The full sequence of ten clips shows the interaction between CaM, calcium ions, the MLCK (myosin light-chain kinase) protein, and the actin-myosin bundles of the cell's cytoskeleton, resulting in contraction of the membrane and cell division. For the entire sequence, see clips K003/3847 to K003/3838. For the same sequence as an anaglyph 3D animation, see clips K003/4492 to K003/4483.
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