RAMON ANDRADE 3DCIENCIA / SCIENCE PHOTO LIBRARY RAMON ANDRADE 3DCIENCIA / SCIENCE PHOTO LIBRARY
Cisplatin drug interaction. Computer artwork showing the structure of a molecule of the chemotherapy drug Cisplatin (centre) coordinated to a section of DNA (deoxyribonucleic acid) containing two guanine bases. This drug is used to treat a number of cancers, including sarcomas, lymphomas and ovarian cancer. It slows the growth of the cancer by damaging the DNA (deoxyribonucleic acid) in the cancerous cells. It causes cross-linking between DNA strands (seen here), which prevents the cells from dividing. The cells try to repair this damage, but are unable to do so and so initiate apoptosis (programmed cell death).
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