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Mast cell, TEM

Mast cell, TEM

C015/1047

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Credit

MICROSCAPE / SCIENCE PHOTO LIBRARY MICROSCAPE / SCIENCE PHOTO LIBRARY

Caption

Mast cell. Transmission electron micrograph (TEM) of section through a mast cell in connective tissue. Mast cells are specialised white blood cells (leukocytes) that settle in connective tissue and usually do not circulate in blood. The large dense granules (dark circles) in the cell cytoplasm contain many biologically important molecules including histamine, which causes tissue swelling in inflammatory reactions, and heparin, which acts as an anticoagulant. The typical symptoms of an allergic reaction are due in large part to the release of mast cell granules. Magnification: x6,000 when printed 10 centimetres wide.

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