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Liver cells affected by haemosiderosis

Liver cells affected by haemosiderosis

M170/0078

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26.5 MB (2.7 MB compressed)

3735 x 2480 pixels

31.5 x 21.1 cm ⏐ 12.4 x 8.3 in (300dpi)

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Credit

ASTRID & HANS-FRIEDER MICHLER / SCIENCE PHOTO LIBRARY. ASTRID & HANS-FRIEDER MICHLER / SCIENCE PHOTO LIBRARY.

Caption

Light micrograph of a section of the human liver affected by haemosiderosis, a condition characterized by the excessive deposition of iron in the liver and caused by a high dietary intake or following repeated blood transfusions. Iron is stored as haemosiderin in the Kuppfer cells and hepatocytes (liver cells) and causes liver cell death and cirrhosis. Here, some cells contain large quantities of iron which is stained blue by Perls stain. A comparable condition, haemochromatosis, results from an inherited defect in iron metabolism & affects other organs in addition to the liver. Magnification: x50 (35mm).

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