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Trapping C. elegans

Trapping C. elegans

C016/6578

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Credit

JAMES KING-HOLMES / SCIENCE PHOTO LIBRARY JAMES KING-HOLMES / SCIENCE PHOTO LIBRARY

Caption

Chungxiao Hu, an electrical engineer at the University of Southampton test a device which holds a 1 millimetre-long Caenorhabditis elegans nematode. It has been found possible to record the brain activity of these tiny creatures and it is hoped such information can be used as a high-throughput screening technology for neuroactive and neurotoxic pharmacology compounds.The device, currently the size of a microscope slide, was developed by electronics engineer Chunxiao Hu and Professor Lindy Holden-Dye of the University's neuroscience electrophysiology department. Using a series of micro-valves it introduces one nematode at a time into a space where it is held in place whilst neuronal activity is measured under various conditions.

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