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Trapping C. elegans

Trapping C. elegans

C016/6581

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50.3 MB (50.0 MB compressed)

5360 x 3280 pixels

45.5 x 27.7 cm ⏐ 17.9 x 10.9 in (300dpi)

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Credit

JAMES KING-HOLMES / SCIENCE PHOTO LIBRARY JAMES KING-HOLMES / SCIENCE PHOTO LIBRARY

Caption

False-colour image of a 1 millimetre-long nematode worm, Caenorhabditis elegans being held securely, but without causing it damage, in a device developed at the University of Southampton which allows scientists to record the neuronal 'brain' activity of these tiny creatures. It is hoped such information can be used as a high-throughput screening technology for neuroactive and neurotoxic compounds.The device, the size of a microscope slide, was developed by a multidisciplinary team of engineers and neuroscientists at the University of Southampton's Life Sciences Institute led by Professor Lindy Holden-Dye. Electronics engineer Chunxiao Hu optimised the microfluidic chamber which uses a series of micro-valves. This introduces one nematode at a time into a precision engineered channel where it is held in place whilst neuronal activity is measured under various conditions.

Release details

Model release not required. Property release not required.

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