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Superficial pemphigus, light micrograph

Superficial pemphigus, light micrograph

C016/6719

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Credit

ISM / SCIENCE PHOTO LIBRARY ISM / SCIENCE PHOTO LIBRARY

Caption

Superficial pemphigus. Light micrograph of a section through a blister on the skin of a patient with pemphigus. Pemphigus is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes. It causes autoantibodies to attack desmoglein, the 'glue' that attaches adjacent epidermal (skin) cells via points called desmosomes. When autoantibodies attack desmogleins, the cells become separated from each other and the epidermis becomes 'unglued' (acantholysis). This causes blisters that slough off and turn into sores. Magnification: x280, when printed 10 centimetres wide.

Release details

Model release not required. Property release not required.

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