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Sirtuin enzyme and p53, artwork

Sirtuin enzyme and p53, artwork

C017/3658

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Credit

RAMON ANDRADE 3DCIENCIA / SCIENCE PHOTO LIBRARY RAMON ANDRADE 3DCIENCIA / SCIENCE PHOTO LIBRARY

Caption

Sirtuin enzyme and p53. Computer artwork of a sirtuin (Sir2) enzyme (pink) bound to a p53 peptide (orange). Sir2 enzymes form a unique class of NAD(+)-dependent deacetylases that are required for diverse biological processes, including transcriptional silencing, regulation of apoptosis (programmed cell death), fat mobilisation, and lifespan regulation. NAD is shown as a stick model (centre). DNA.

Release details

Model release not required. Property release not required.

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