FRANCIS LEROY & VALERIE ROUVROY, BIOCOSMOS / SCIENCE PHOTO LIBRARY FRANCIS LEROY & VALERIE ROUVROY, BIOCOSMOS / SCIENCE PHOTO LIBRARY
Nuclear membrane during nuclear division (mitosis). The nuclear membrane breaks down during mitosis to allow two daughter nuclei to be formed from the replicating nucleus. The nuclear lamina (green) becomes phosphorylated (grey spheres) and the nuclear membrane breaks into segments. At the same time the DNA (deoxyribonucleic acid, red) condenses into chromosomes. When the replicated chromosomes have moved to separate poles a nuclear membrane reforms at each pole to make a new nucleus. Repolymerisation of the lamina and the subsequent fusion of membrane vesicles is thought to be induced by dephosphorylation of the lamina.
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