STEVE GSCHMEISSNER / SCIENCE PHOTO LIBRARY STEVE GSCHMEISSNER / SCIENCE PHOTO LIBRARY
Temporal arteritis, light micrograph of a section of an affected vessel. Temporal arteritis (Horton's disease) is a condition in which medium and large arteries, usually in the head and neck, become inflammed. The condition is one of the most common types of vasculitis, which is the general term for the inflammation of arteries and veins. The most serious complication of temporal ateritis is permanent blindness, though this can be prevented by prompt treatment with corticosteroids. The cause of the condition is unknown. It is believed to be due in part to a faulty immune response. The disorder has been linked to severe infections and the use of high doses of antibiotics. Inflammatory cell infiltrate includes macrophages, lymphocytes, plasma cells and often giant cells. The lumen is severely narrowed. Magnification: x 80 when printed at 10 centimetres wide. Human tissue.
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