FRANCIS LEROY & VALENTIN LEGRAND, BIOCOSMOS / SCIENCE PHOTO LIBRARY FRANCIS LEROY & VALENTIN LEGRAND, BIOCOSMOS / SCIENCE PHOTO LIBRARY
Glyoxalate metabolic cycle. Animated diagram of the anabolic metabolic cycle used by plants to synthesize carbohydrates from fatty acids (the glyoxalate cycle). This is a variant of the tricarboxylic acid cycle. Here, acetyl-Coenzyme A combines with oxalacetate to form a 6-carbon compound, citrate. This metabolite is then converted into isocitrate. However, instead of being degraded by the two following steps of the citric cycle, isocitrate is directly converted into succinate and glyoxalate. Glyoxalate then reacts with another acetyl-CoA to yield malate. Malate is also produced from succinate via a reaction with fumarate. The malate and oxaloacetate are used for the synthesis of the simple sugar glucose (coloured molecule, upper left).
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