STEVE GSCHMEISSNER / SCIENCE PHOTO LIBRARY STEVE GSCHMEISSNER / SCIENCE PHOTO LIBRARY
Juvenile xanthogranuloma. Light micrograph of affected skin from a child. Juvenile xanthogranuloma (JXG) primarily is a self-limited dermatologic tumour that is associated rarely with systemic manifestations. Infants and small children are mainly affected. As it is harmless and tends to clear away on its own in children, treatment is not recommended except if it affects the eyes. Characteristic touton giant cells are visible (large purple cells) which are formed by the fusion of epithelioid cells (macrophages), and contain a ring of nuclei surrounded by a foamy cytoplasm. Magnification: x 150 when printed at 10 centimetres wide. Human tissue.
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