FRANCIS LEROY & OLIVIER WAUTIER, BIOCOSMOS / SCIENCE PHOTO LIBRARY FRANCIS LEROY & OLIVIER WAUTIER, BIOCOSMOS / SCIENCE PHOTO LIBRARY
Nuclear protein export, animation. The movement of small molecules such as proteins out of the nucleus (bottom left) is regulated by nuclear pore complexes (top left) in the nuclear membrane. Proteins that are to be transported from the nucleus are tagged with nuclear export signals (NES, yellow). Proteins called exportins (purple) bind to this tag and to ran-GTP (guanosine triphosphate) to facilitate the protein's movement through a nuclear pore (light blue). Once in the cytoplasm the three separate. This allows the hydrolysis of GTP to GDP (guanosine diphosphate) and inorganic phosphate (Pi).
Model release not required. Property release not required.