CAROL AND MIKE WERNER / SCIENCE PHOTO LIBRARY CAROL AND MIKE WERNER / SCIENCE PHOTO LIBRARY
Labelled illustration of Mast cells. Mast cells, activated by allergens binding with IgE on the cell surface, react by discharging preformed mediators such as histamine and cytokines. A part of the immune system, mast cells reside in several types of tissue, particularly those associated with blood vessels, nerves and epithelial cells. They contain many granules filled with histamine and heparin. They play an important role in allergy and anaphylaxis as well as wound healing and defence against pathogens.
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