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Insulin glargine structural formula

Insulin glargine structural formula

C022/4905

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Credit

CAROL & MIKE WERNER / VISUALS UNLIMITED, INC. / SCIENCE PHOTO LIBRARY CAROL & MIKE WERNER / VISUALS UNLIMITED, INC. / SCIENCE PHOTO LIBRARY

Caption

Insulin glargine structural formula illustration. Insulin glargine is a recombinant human insulin analogue produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. Insulin glargine differs from human insulin in that the amino acid asparagine at position A21 is replaced by glycine and two arginines are added to the C-terminus of the B-chain. Pink=A-chain, light brown=B-chain, yellow=sulfur, red=differences from human insulin.

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