FRANCIS LEROY & MAXIME DEROYER, BIOCOSMOS / SCIENCE PHOTO LIBRARY FRANCIS LEROY & MAXIME DEROYER, BIOCOSMOS / SCIENCE PHOTO LIBRARY
Animation showing how steroid hormones can effect genetic expression. The hormone (green) binds to a receptor (purple), in this case a G protein-coupled receptor, in the cell membrane. The hormone-receptor complex binds to the G protein (red and yellow) and induces the release of GDP (guanosine diphosphate) from the protein. This allows GTP (guanosine triphosphate) to bind to the G protein instead, causing the alpha subunit (red) of the G protein to disassociate from the beta/gamma subunit (yellow). The alpha subunit-GTP complex can then activate a number of pathways in the cell that lead to the activation or suppression of transcription of DNA (deoxyribonucleic acid, grey helix) in the nucleus (bottom).
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