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Synthetic ribonuclease molecule

Synthetic ribonuclease molecule

A605/0213

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Credit

DR MARK J. WINTER / SCIENCE PHOTO LIBRARY DR MARK J. WINTER / SCIENCE PHOTO LIBRARY

Caption

Synthetic ribonuclease molecule. Molecular model showing the secondary structure of amphinase, a synthetic version of a ribonuclease molecule found in the egg cells of the northern leopold frog (Rana pipiens). Ribonucleases are enzymes that break up RNA (ribonucleic acid), a molecule used to translate genes into their protein products. Amphinase attaches to glycoproteins on a cell, before invading the cell and killing it by destroying its RNA. Here the amphinase molecule is attached to NAG (N-acetyl-D-Glucosamine, ball and stick structure) a human glycoprotein. Amphinase could potentially be used as an anti-tumour drug, as tumours (especially brain tumours) are covered in glycoproteins (unlike healthy cells).

Release details

Model release not required. Property release not required.

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