NATIONAL LIBRARY OF MEDICINE / SCIENCE PHOTO LIBRARY NATIONAL LIBRARY OF MEDICINE / SCIENCE PHOTO LIBRARY
Breast cancer patient, 19th-century Japan. Illustration of Kan Aiya, a 60-year-old woman from Japan with breast cancer. The cancer was successfully removed on 13 October 1804 by Japanese surgeon Hanaoka Seishu (1760-1835). Hanaoka pioneered the use of general anaesthesia to remove tumours from cancer patients. He used mafutsusan to anaesthetize Kan Aiya, in what is recognised as the world's first surgical procedure under general anaesthesia. Illustration by Tangetsu from 'A Surgical Casebook', a manuscript commissioned by Hanaoka. This illustration is part of a sequence showing the breast cancer surgery and tumour.
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