NATIONAL LIBRARY OF MEDICINE / SCIENCE PHOTO LIBRARY NATIONAL LIBRARY OF MEDICINE / SCIENCE PHOTO LIBRARY
Excised breast cancer, 19th-century Japan. Illustration of a dissected tumour excised in a breast cancer operation carried out on 13 October 1804 by Japanese surgeon Hanaoka Seishu (1760-1835). Hanaoka pioneered the use of general anaesthesia in cancer surgery. He used mafutsusan to anaesthetize 60-year-old Kan Aiya, in what is recognised as the world's first surgical procedure under general anaesthesia. Illustration by Tangetsu from 'A Surgical Casebook', a manuscript commissioned by Hanaoka. This illustration is part of a sequence showing the breast cancer surgery and tumour. Here, the excised tumour has been dissected.
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