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Cell releasing histamine, illustration

Cell releasing histamine, illustration

C023/3529

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Credit

HARVINDER SINGH / SCIENCE PHOTO LIBRARY HARVINDER SINGH / SCIENCE PHOTO LIBRARY

Caption

Mast cell releasing histamine (blue bubbles) in a blood vessel, computer illustration. Mast cells are a type of leucocyte (white blood cell). They contain the chemical mediators histamine, serotonin and heparin. Histamine is released from mast cells in response to an allergen, causing a localized inflammatory immune response. When an allergen is encountered, B cells (not seen) produce antibodies which bind to protein receptor molecules on the surface of the mast cell. When two antibodies are cross-linked with an antigen the cell is activated to release its histamine by exocytosis. Histamine causes capillaries to dilate, smooth muscle to contract, and many other effects.

Release details

Model release not required. Property release not required.

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