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Krebs metabolic cycle for fuel oxidation in mitochondria in eukaryotic cells. At top, pyruvate, produced by an earlier reaction, passes into the mitochondrion where it is converted to acetyl CoA (acetyl coenzyme A). The resulting reactions, also called the citric acid cycle, release carbon dioxide (CO2) and move energy in the form of molecules such as ATP (adenosine triphosphate), ADP (adenosine diphosphate), GTP (guanosine triphosphate), GDP (guanosine diphosphate), NADH/NAD+ (nicotinamide adenine dinucleotide) and FADH2/FAD (flavin adenine dinucleotide). Water (H2O) is also shown in this 9-step cycle, with the orange dots indicating the number of carbon atoms.
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