MICROSCAPE / SCIENCE PHOTO LIBRARY MICROSCAPE / SCIENCE PHOTO LIBRARY
Light microscopy of precursor cancer cells in the adult human testis, often referred to as carcinoma-in-situ or CIS. These pre-cancerous cells have large round nuclei with multiple clumps of chromatin, and a pale cytoplasm stained pink representing glycogen. Usually found around the inner margin of the affected seminiferous tubule which has no normal germ cells or sperm production. In this specimen some CIS cells have invaded the tissue outside of the tubule. The cause of CIS of the testis is not known. These cells are thought to be abnormal primitive germ cells that arise during fetal development. Magnification x500 when printed at 10 cm.
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