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LDL bound to receptors, illustration

LDL bound to receptors, illustration

C026/3493

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Credit

MAURIZIO DE ANGELIS / SCIENCE PHOTO LIBRARY MAURIZIO DE ANGELIS / SCIENCE PHOTO LIBRARY

Caption

LDL bound to receptors. Computer illustration of low-density lipoprotein (LDL), or 'bad' cholesterol, molecules (round) bound to LDL receptor (LDLR) proteins (Y-shaped) in a cell surface (bottom). Each molecule consists of a core of esterified cholesterol molecules surrounded by a shell (green and yellow) of unesterified cholesterol and phospholipids. The complex structure includes carrier proteins (thread-like) known as apo-B proteins, which assist transport in the blood. When there are high levels of LDL cholesterol in the blood it builds up on the sides of blood vessels hardening them, a condition named atherosclerosis. This narrows the blood vessels and may block them. LDL receptors recognise and bind to LDL molecules to remove them from the bloodstream.

Release details

Model release not required. Property release not required.

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