MONICA SCHROEDER / SCIENCE PHOTO LIBRARY MONICA SCHROEDER / SCIENCE PHOTO LIBRARY
An illustration of an islet of Langerhans in the pancreas. Langerhans' cells are located in all layers of the epidermis but are most easily seen in the prickle cell layer. They recognize antigens and are an important component of the immune system. Ultrastructurally, Langerhans' cells have an irregular clefted nucleus and are devoid of tonofilaments. They have prominent mitochondria, lysosmes and rough endoplasmic reticulum.
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