DON W. FAWCETT / SCIENCE PHOTO LIBRARY DON W. FAWCETT / SCIENCE PHOTO LIBRARY
Colour enhanced transmission electron micrograph of freeze-fractured gap junctions. Gap junctions are isolated from mouse liver cells and examined by negative staining using phosphotungstate or uranyl formate as the contrast medium. At high magnification, the 8 to 9 nm particles or connexons have central 1.5 to 2nm electron-dense region which is believed to represent the polar channel through which cell to cell communication takes place.
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