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LDL bound to receptor, illustration

LDL bound to receptor, illustration

F012/9131

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Credit

JUAN GAERTNER / SCIENCE PHOTO LIBRARY JUAN GAERTNER / SCIENCE PHOTO LIBRARY

Caption

LDL bound to receptor. Computer illustration of a low-density lipoprotein (LDL), or 'bad' cholesterol, molecule (round) bound to an LDL receptor (LDLR) protein (pink) in a cell membrane (bottom). The LDL molecule consists of a core of esterified cholesterol molecules surrounded by a shell of unesterified cholesterol and phospholipids. The complex structure includes carrier proteins (blue) known as apo-B proteins, which assist transport in the blood. When there are high levels of LDL cholesterol in the blood it builds up on the sides of blood vessels hardening them, a condition named atherosclerosis. This narrows the blood vessels and may block them. LDL receptors recognise and bind to LDL molecules to remove them from the bloodstream.

Release details

Model release not required. Property release not required.

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