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RNA-editing enzyme combined with RNA

RNA-editing enzyme combined with RNA

A617/0279

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Credit

LAGUNA DESIGN / SCIENCE PHOTO LIBRARY LAGUNA DESIGN / SCIENCE PHOTO LIBRARY

Caption

RNA-editing enzyme combined with RNA. Computer model showing the mRNA-editing enzyme, APOBEC-1 (apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1), interacting with mRNA (messenger ribonucleic acid). APOBEC enzymes catalyse the breakdown (deamination) of the amino acid cytidine in nucleic acids (DNA - deoxyribonucleic acid, and RNA), changing it to uridine. APOBEC-1 works in conjuction with ACF (APOBEC-1 complementation factor). Different APOBEC members use this deamination process to achieve diverse human biological functions, such as inhibiting the replication of HIV.

Release details

Model release not required. Property release not required.

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