DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY
Liver polygonal hepatocytes and sinusoid area, coloured scanning electron micrograph (SEM). Hepatocytes (liver cells) have a polyhedral shape and are arranged in layers, called hepatic laminae that typically are one-cell thick. Hepatocytes secrete bile that carries away waste products from the liver and helps the breakdown of fats in the small intestine. Bile is drained away in the bile canaliculi (green) and is stored in the gall bladder. Hepatocytes manufacture serum albumin, fibrinogen, and the prothrombin group of clotting factors. The liver is the main site for the synthesis of lipoproteins, ceruloplasmin, transferrin, complement, and glycoproteins. Hepatocytes manufacture their own structural proteins and intracellular enzymes. Synthesis of proteins is by the rough endoplasmic reticulum (RER), and both the rough and smooth endoplasmic reticulum (SER) are involved in secretion of the proteins formed. Magnification: x700 when shortest axis.
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