This image is not available for purchase in your country.

Extracellular matrix, SEM

Extracellular matrix, SEM

C032/0804

Rights Managed

This image is not available for purchase in your country.

Please contact your Account Manager if you have any query.

Credit

DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY

Caption

Extracellular matrix (ECM) produced by dermal fibroblasts, coloured scanning electron micrograph (SEM).The ECM is a complex structural tissue component surrounding and supporting cells in mammalian tissues. It is composed of 3 major classes of biomolecules: 1) Structural proteins - collagen and elastin, 2) Specialized proteins - such as: fibrillin, fibronectin, and laminin and 3) Proteoglycans - complex proteins and long chains of repeating disaccharide units called glycosaminoglycans (GAGs, such as: hyaluronic acid, chondroitin sulphate, heparin, heparan sulphate). Collagens are the most abundant proteins found in the animal kingdom. It is the major protein comprising the ECM. Many cells bind to components of the extracellular matrix. The cell to ECM adhesion is regulated by specific cell surface cellular adhesion molecules (CAM) known as integrins. The integrins transmit mechanical stimuli from the ECM to the cytoskeleton. Magnification: x1,000.

Release details

Model release not required. Property release not required.

 {{ i.shot_duration ? i.shot_duration + ' ' : '' }}{{ i.shot_uhd ? '4K ' : i.hires ? 'HD ' : '' }}{{ i.spl_number }} R{{ i.license }}

  • Add to board
  • Similar {{ mediaType(i) }}