DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY
Light micrograph (LM) of Streptomycin (antibiotic) crystals. Streptomycin was the first of a class of drugs called aminoglycosides to be discovered and was the first antibiotic remedy for tuberculosis. It is derived from a soil bacterium (actinobacterium, actinomycete bacterium) called Streptomyces griseus. Streptomycin acts by inhibiting protein synthesis and damaging cell membranes in susceptible microorganisms. It is used in fighting Gram-positive and Gram-negative bacterial infections, including species resistant to other antibiotics. Streptomycin cannot be given orally, but must be administered by intramuscular injection. Side effects include nausea, dizziness, kidney toxicity and hearing loss. Magnification: x40 when shortest axis printed at 25 millimetres.
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