DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY
Light micrograph (LM) of Neomycin crystals. Neomycin is an antibiotic that is produced naturally by the actinomycete bacterium Streptomyces fradiae. Neomycin has a broad spectrum of effect, killing both Gram-positive and Gram-negative bacteria. It is relatively toxic to humans, and some people have allergic reactions to it. It is found in many topical medications such as creams, ointments and eye drops. It can also be given orally, where it is usually combined with other antibiotics. Neomycin is not absorbed from the gastrointestinal tract, and has been used as a preventative measure for hepatic encephalopathy and hypercholesterolemia. By killing bacteria in the intestinal tract, it keeps ammonia levels low and prevents hepatic encephalopathy, especially prior to gastrointestinal surgery. It is not given intravenously, as neomycin is extremely nephrotoxic, especially compared to other aminoglycosides. Magnification: x40 when shortest axis printed at.
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