DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY
Coloured scanning electron micrograph (SEM) of Scedosporium prolificans, a dematiaceous filamentous fungus isolated from soil samples and infected patients. Colonies of S. prolificans grow rapidly and consist of filamentous hyaline hyphae. Asexual conidiogenous cells (conidia) called annelides (orange) form at the end of hyaline hyphae. S. prolificans is a human pathogen causing many different human fungal diseases. Subcutaneous infections, osteomyelitis, and arthritis are usually posttraumatic and may affect otherwise healthy individuals. S. prolificans is now recognized as the most common cause of disseminated phaeohyphomycosis. Colonization of the external ear, paranasal sinuses and lung, including fungus ball (tumour like mass of fungi) have been reported. Cases with pneumonia, meningoencephalitis and endocarditis have also been reported. S. prolificans is resistant to many fungicides. Magnification: x665 when shortest axis printed at 25.
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