JACOPIN / BSIP / SCIENCE PHOTO LIBRARY JACOPIN / BSIP / SCIENCE PHOTO LIBRARY
Illustration of the principle of CAR-T cell immunotherapy consisting of modifying some of the patients immune cells, T lymphocytes, so that they directly and specifically recognize the tumour cells and attack them. T lymphocytes are removed and genetically modified (CAR-T cells) so that they will specifically recognize certain diseased cells. CAR-T cells bond with the cancer cells which triggers various activities (the production of cytokines, expansion of lymphocytes etc.) contributing to the destruction of the cancer cells.
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