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Differentiating stem cell from cord blood, SEM

Differentiating stem cell from cord blood, SEM

C036/9894

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Credit

DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY

Caption

Differentiating stem cell (CD34+) from umbilical cord blood, scanning electron micrograph (SEM). Shown here is the first stage of a CD34+ stem cell differentiating in to another blood cell type. Note the new protoplasmic bulge forming at one position on the stem cell periphery; this new growth extension of the cell is the first morphological sign of the stem cell developing in to another cell type. CD34+ stem cells are normally found in the umbilical cord and bone marrow as hematopoietic stem cells. They are multipotent; they differentiate to produce precursor (progenitor) cells of any of the body's blood cell types. This process of stem cell differentiation in the circulatory system is called hemopoiesis. CD34 is a cell surface glycoprotein and functions as a cell-cell adhesion factor. Magnification: x2,600 when shortest axis printed at 25 millimeters.

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