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Human dendritic cells, SEM

Human dendritic cells, SEM

C037/0651

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Credit

DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY DENNIS KUNKEL MICROSCOPY / SCIENCE PHOTO LIBRARY

Caption

Scanning electron micrograph (SEM) of human dendritic cells grown in suspension (PBX Fix B) showing lamellipodia and filipodia. Dendritic cells (also known as histiocytes or Langerhans cells in the epidermis) are part of the immune system. They are macrophage cells that are found in the body's tissues. The long extensions seen projecting from the cell help them to move. The dendritic cells recognize and engulf foreign cells and proteins (antigens) and act as antigen presenting cells (APCs) that present the digested parts of phagocytosed pathogens to other immune system cells to enhance the immune response. Once activated, the dendritic cells migrate to the lymphoid tissues where they interact with T cells and B cells to initiate and shape the adaptive immune response. Magnification: x7,000 when shortest axis printed at 25 millimetres.

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