KATERYNA KON / SCIENCE PHOTO LIBRARY KATERYNA KON / SCIENCE PHOTO LIBRARY
Cirrhotic liver with hepatocellular carcinoma, computer artwork. One of the causes of hepatocellular carcinoma is viral infection, particularly with hepatitis C viruses (HCV). Hepatitis C is a common cause of chronic hepatitis which progresses to liver cirrhosis. Viruses cause cell death (necrosis) in the hepatic lobules, which leads to scarring. This causes the liver surface to appear rough and lumpy instead of the usual smooth healthy appearance. The disease is irreversible and may lead to liver carcinoma.
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