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Papillomatosis in Cowden's disease. Close-up of the mouth of a 12-year-old boy, showing the presence of papillomatosis on the buccal mucosa in a case of Cowden's disease. Papillomatosis is the enlargement of the dermal papillae. Cowden's disease (also called Cowden syndrome and multiple hamartoma syndrome) is a genetic condition where a mutation causes the development of non-cancerous tumour-like growths called hamartomas.
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