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Perianal ulcerations in Crohn's disease. Close-up of ulcers that have formed in the perianal region (around the anus) in a 49-year-old man with Crohn's disease (regional enteritis). Crohn's disease causes inflammation, thickening, and ulceration of the intestinal tract. Its cause is unknown. Symptoms include abdominal pain, diarrhoea and weight loss.
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