LAGUNA DESIGN / SCIENCE PHOTO LIBRARY LAGUNA DESIGN / SCIENCE PHOTO LIBRARY
Calcifediol molecule. Computer model showing the structure of a molecule of the pre-hormone calcifediol. Atoms are colour-coded (carbon: grey, hydrogen: white, oxygen: red) with the bonds between them shown as sticks. Calcifediol is produced by hydroxylation of vitamin D3 (cholecalciferol) in the liver. It is then converted by an enzyme in the kidneys into calcitriol, a secosteroid hormone and the active form of vitamin D. Because of its close involvement in the metabolism of vitamin D, blood concentration of calcidiol is considered the best indicator of vitamin D status in the body.
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