KENNETH EWARD / SCIENCE PHOTO LIBRARY KENNETH EWARD / SCIENCE PHOTO LIBRARY
The enzyme HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) reductase, shown here as a ribbons model, catalyzes a crucial step in the synthesis of cholesterol. This enzyme is inhibited by statin drugs, blocking cholesterol synthesis. This HMG-CoA reductase is inhibited by the statin fluvastatin, bound to its active site.
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