NATURE'S FACES / SCIENCE SOURCE / SCIENCE PHOTO LIBRARY NATURE'S FACES / SCIENCE SOURCE / SCIENCE PHOTO LIBRARY
Pelger-Huet anomaly is a benign dominantly inherited defect of terminal neutrophil differentiation secondary to mutations in the lamin B receptor (LBR) gene. Some leukocytes appear as dumbbell-shaped bilobed nuclei (as shown here). Light micrograph, Wright-Giemsa stain. Magnification: 100x.
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